![Integrate-C Fusion System HAPPE](https://happeortho.com/wp-content/uploads/2023/05/Integrate-C-Fusion-System-HAPPE-2-.png)
Integrate (verb):
to combine two or more things in order to become more effective
Powered by the HAPPE® platform, INTEGRATE®-C is the first interbody fusion cage to offer cancellous porosity with fully integrated hydroxyapatite through the entire implant height, combined with radiolucency and bone-like mechanical properties.
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Porous and Dense Material
INTEGRATE® has porous and dense material designed for optimum biomechanics in load bearing and healing.
![](https://happeortho.com/wp-content/uploads/2022/10/Cancellous-porosity-for-bone-ingrowth-3.jpg)
Interconnected Cancellous Porosity
INTEGRATE® has interconnected cancellous porosity for bone ingrowth endplate-to-endplate.
![](https://happeortho.com/wp-content/uploads/2022/10/HAPPE-Spine-radiolucent-and-radiovisible2.jpg)
Radiolucent and Radiovisible
INTEGRATE® is both radiolucent and radiovisible for superior post-operative imaging.
MATERIAL CHOICES AVAILABLE IN INTERBODY FUSION
![HAPPE material property comparison](https://happeortho.com/wp-content/uploads/2023/05/HAPPE-comparison-chart-4.jpg)
Bone ingrowth into HAPPE implants was confirmed in an ovine cortical bone defect model.*
![Bone ingrowth into HAPPE implants](https://happeortho.com/wp-content/uploads/2022/09/Bone-ingrowth-into-HAPPE-implants-.jpg)
*R.K. Roeder, J.F. Nagle and D. Snell, “Translating Porous and Bioactive PEEK to Interbody Spinal Fusion Implants,” Society for Biomaterials Annual Meeting, 2021. University of New South Wales – Surgical & Orthopaedic Research Laboratories – Evaluation of osteointegration in a large animal model. Note: the porous structure of the HAPPE® material in the INTEGRATE®-C Fusion Device has been modified from that used for this ovine study with the intent to further increase pore interconnectivity for bone in-growth. In vitro performance or animal studies may not be representative of clinical performance.
The INTEGRATE-C Fusion System
![Inserting INTEGRATE™-C Fusion Device into the spine](https://happeortho.com/wp-content/uploads/2022/09/INTEGRATE™-C-Fusion-Device.jpg)
The INTEGRATE®-C Fusion Device is made of a single, continuous piece of hydroxyapatite impregnated polyetheretherketone polymer.
The INTEGRATE®-C Fusion Device is monolithic with porous regions derived directly from the implant body, not a sintered or otherwise additive coating, and extended through the device.
The device is available in a variety of footprints, lordosis and heights to accommodate variations in the individual pathology and anatomy of the patient. The superior and inferior surfaces of the device contain a pattern of teeth to provide for initial stability. Radiopaque markers are placed in the device to aid in determining the location of the implant intra- and post-operatively.
Features and Benefits
![](https://happeortho.com/wp-content/uploads/2024/03/Screenshot-2024-03-04-at-8.23.34 PM.jpg)
- Made with patented HydroxyApatite Porous PolyEtheretherketone (HAPPE®)
- Large graft space lined with porous HAPPE material for endplate-to-endplate osteointegration
- Dense structural element for load bearing and impaction
- Exposed hydroxyapatite crystals throughout the implant for hydrophilic surfaces
- Implant sizes include 15 x 12, 17 x 14 and 20 x 15 mm with 7 or 10 degree lordosis for anatomic fit
- Tapered design for easy insertion and aggressive teeth for preventing expulsion
- Tantalum markers for radiographic visualization
- Radiolucent for post-operative assessment of fusion
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